Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15725306 | 0.95 | ESR2 (0.44) | ESR2NOTUMCYP19A1STSALOX5AP | |
| SCHEMBL12662767 | 0.95 | ESR2 (0.44) | ESR2NOTUMCYP19A1STSALOX5AP | |
| SCHEMBL13987419 | 0.94 | ESR2 (0.37) | ESR2CYP19A1STSALOX5APFEN1 | |
| SCHEMBL24203140 | 0.91 | FEN1 (0.33) | NOTUMCYP19A1STSALOX5APFEN1 | |
| SCHEMBL26672879 | 0.89 | ESR2 (0.39) | ESR2NOTUM | |
| SCHEMBL739170 | 0.89 | ESR2 (0.39) | ESR2NOTUM | |
| SCHEMBL26167260 | 0.87 | ESR2 (0.39) | ESR2 | |
| SCHEMBL29322497 | 0.86 | FEN1 (0.37) | NOTUMALOX5APFEN1 | |
| SCHEMBL25929340 | 0.86 | FEN1 (0.35) | NOTUMALOX5APFEN1 | |
| SCHEMBL25929172 | 0.86 | FEN1 (0.35) | NOTUMALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295510-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-09-21 | — | — | US | disclosed |
| US-20230295511-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-09-21 | — | — | US | disclosed |
| US-20230272282-A1 | LC MIXTURES WITH NEGATIVE DELTA EPSILONCONTAINING CC-4-V1 AND COB(S)-N-OM | MERCK PATENT GMBH (DE) | 2023-08-31 | — | — | US | disclosed |
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-08-08 | — | — | US | disclosed |
| US-20230242817-A1 | LIQUID-CRYSTAL MEDIUM COMPRISING POYLMERIZABLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-08-03 | — | — | US | disclosed |
| US-11685863-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-06-27 | — | — | US | disclosed |
| US-20230159825-A1 | LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-05-25 | — | — | US | disclosed |
| US-11655417-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2023-05-23 | — | — | US | disclosed |
| WO-2022129018-A1 | HETEROAROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022128845-A1 | HETEROAROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |
| US-9234136-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2016-01-12 | — | — | US | disclosed |
| US-20140138581-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-05-22 | — | — | US | disclosed |
| US-7854970-B2 | Liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-12-21 | — | — | US | disclosed |
| US-7785677-B2 | Mixture of polar compounds containing cyclohexane and benzene rings some of which are vinylene-linked, especially containing fluoroalkoxy groups; for electrooptical twisted nematic monitor applications | MERCK PATENT GMBH (DE) | 2010-08-31 | — | — | US | disclosed |
| US-20100051864-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT (DE) | 2010-03-04 | — | — | US | disclosed |
| US-20080315157-A1 | Mixture of polar compounds containing cyclohexane and benzene rings some of which are vinylene-linked, especially containing fluoroalkoxy groups; for electrooptical twisted nematic monitor applications | MERCK PATENT GESELLSCHAFT (DE) | 2008-12-25 | — | — | US | disclosed |
| US-20080308768-A1 | Liquid Crystalline Medium | MERCK PATENT GMBH (DE) | 2008-12-18 | — | — | US | disclosed |
| US-7371437-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2008-05-13 | — | — | US | disclosed |
| US-7351453-B2 | Mixture of polar compounds of biphenyls, cyclohexane and phenyl substituted biphenyl; fast response time, a low threshold voltage, low temperature stability | MERCK PATENT GMBH (DE) | 2008-04-01 | — | — | US | disclosed |
| US-20070051920-A1 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | VCL, ILK, LCP1 | ESR2 4146/4885NOTUM 3104/4885CYP19A1 4092/4885 |
| US-11685863-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | LPXN, VCL, LCP1 | ESR2 2906/4885NOTUM 3611/4885CYP19A1 1837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.