Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 19/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211294 | 0.87 | HSD11B1 (0.72) | HSD11B1 | |
| SCHEMBL3219337 | 0.87 | HSD11B1 (0.72) | HSD11B1 | |
| SCHEMBL13039823 | 0.83 | HSD11B1 (0.75) | HSD11B1 | |
| SCHEMBL3630390 | 0.82 | HSD11B1 (0.79) | HSD11B1 | |
| SCHEMBL3225979 | 0.81 | HSD11B1 (0.68) | HSD11B1 | |
| SCHEMBL3219549 | 0.81 | HSD11B1 (0.69) | HSD11B1 | |
| SCHEMBL13039824 | 0.80 | HSD11B1 (0.61) | HSD11B1 | |
| SCHEMBL3220084 | 0.80 | HSD11B1 (0.79) | HSD11B1 | |
| SCHEMBL3657416 | 0.80 | HSD11B1 (0.60) | HSD11B1 | |
| SCHEMBL13039829 | 0.80 | HSD11B1 (0.62) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010141550-A2 | 11-BETA HSD1 INHIBITORS | WYETH LLC (US) | 2010-12-09 | — | — | WO | disclosed |