SCHEMBL13041586

SCHEMBL13041586

C=CC(=O)OCCCCCCOc1ccc2cc(C(=O)Oc3ccc(OC(=O)c4ccc5cc(OCCCCCCOC(=O)C=C)ccc5c4)c(O)c3)ccc2c1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40
THRB P10828 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
THRA P10827 1/20 0.38
LSS P48449 1/20 0.37
MAPT P10636 1/20 0.36
ESR1 P03372 2/20 0.36
KMT2A Q03164 2/20 0.36
ESR2 Q92731 1/20 0.36
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23322797 0.97 HTT (0.41) ALDH1A1CYP3A4TSHRHTTTHRB
SCHEMBL15468744 0.91 HTT (0.44) ALDH1A1CYP3A4TSHRHTTTHRB
SCHEMBL12733887 0.90 THRA (0.39) ALDH1A1CYP3A4TSHRHTTTHRB
SCHEMBL9906491 0.90 THRA (0.39) ALDH1A1CYP3A4TSHRHTTTHRB
SCHEMBL9906494 0.90 THRA (0.39) ALDH1A1CYP3A4TSHRHTTTHRB
SCHEMBL9906492 0.90 TSHR (0.39) ALDH1A1CYP3A4TSHRHTTTHRB
SCHEMBL22131047 0.89 POLB (0.41) TSHRHTTTHRBESR1KMT2A
SCHEMBL9906498 0.89 THRA (0.39) ALDH1A1CYP3A4TSHRHTTTHRB
SCHEMBL815927 0.89 MAPT (0.45) CYP3A4HDAC6MAPTKMT2AMEN1
SCHEMBL15398137 0.89 THRA (0.41) ALDH1A1CYP3A4TSHRHTTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2261201-A1 TRIFUNCTIONAL (METH)ACRYLATE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE COMPOUND Adeka Corporation (JP) 2010-12-15 EP disclosed