Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.70 |
| ▸ | CA1 | P00915 | 11/20 | 0.70 |
| ▸ | CA9 | Q16790 | 9/20 | 0.70 |
| ▸ | CA5A | P35218 | 8/20 | 0.70 |
| ▸ | CA5B | Q9Y2D0 | 8/20 | 0.70 |
| ▸ | CA12 | O43570 | 6/20 | 0.70 |
| ▸ | CA3 | P07451 | 3/20 | 0.70 |
| ▸ | CA4 | P22748 | 3/20 | 0.70 |
| ▸ | CA6 | P23280 | 3/20 | 0.70 |
| ▸ | CA7 | P43166 | 3/20 | 0.70 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.70 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3734129 | 0.90 | CA2 (0.69) | CA2CA1CA9CA5ACA5B | |
| SCHEMBL3734123 | 0.90 | CA2 (0.69) | CA2CA1CA9CA5ACA5B | |
| SCHEMBL3743198 | 0.89 | CA2 (0.68) | CA2CA1CA9CA5ACA5B | |
| SCHEMBL3743205 | 0.89 | CA2 (0.68) | CA2CA1CA9CA5ACA5B | |
| SCHEMBL13012579 | 0.89 | CA2 (0.65) | CA2CA1CA9CA5ACA5B | |
| SCHEMBL13042268 | 0.88 | CA2 (0.67) | CA2CA1CA9CA5ACA5B | |
| SCHEMBL3727950 | 0.86 | CA2 (0.69) | CA2CA1CA9CA5ACA5B | |
| SCHEMBL18475606 | 0.86 | CA2 (0.68) | CA2CA1CA9CA5ACA5B | |
| SCHEMBL3727945 | 0.86 | CA2 (0.69) | CA2CA1CA9CA5ACA5B | |
| SCHEMBL13012577 | 0.85 | CA2 (0.62) | CA2CA1CA9CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829063-B2 | Development of molecular imaging probes for carbonic anhydrase-IX using click chemistry | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2010-11-09 | — | — | US | disclosed |