Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.42 |
| ▸ | CA1 | P00915 | 14/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | IL1RN | P18510 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3775757 | 1.00 | CA2 (0.42) | CA2CA1CA12CA7CA9 | |
| SCHEMBL3775761 | 1.00 | CA2 (0.42) | CA2CA1CA12CA7CA9 | |
| SCHEMBL3740196 | 0.95 | CA1 (0.42) | CA2CA1CA12CA7CA9 | |
| SCHEMBL3734673 | 0.95 | CA1 (0.42) | CA2CA1CA12CA7CA9 | |
| SCHEMBL3734677 | 0.95 | CA1 (0.42) | CA2CA1CA12CA7CA9 | |
| SCHEMBL3737706 | 0.95 | CA1 (0.42) | CA2CA1CA12CA7CA9 | |
| SCHEMBL4554498 | 0.90 | CA2 (0.42) | CA2CA1CA12CA7CA9 | |
| SCHEMBL4554500 | 0.90 | CA2 (0.42) | CA2CA1CA12CA7CA9 | |
| SCHEMBL3734877 | 0.89 | CA1 (0.41) | CA2CA1CA12CA7CA9 | |
| SCHEMBL3734875 | 0.89 | CA1 (0.41) | CA2CA1CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829063-B2 | Development of molecular imaging probes for carbonic anhydrase-IX using click chemistry | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2010-11-09 | — | — | US | disclosed |