Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 20/20 | 0.42 |
| ▸ | CA1 | P00915 | 15/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3734834 | 1.00 | CA2 (0.42) | CA2CA1CA12CA7CA9 | |
| SCHEMBL13012337 | 1.00 | CA2 (0.42) | CA2CA1CA12CA7CA9 | |
| SCHEMBL3770182 | 1.00 | CA2 (0.42) | CA2CA1CA12CA7CA9 | |
| SCHEMBL10181791 | 1.00 | CA2 (0.42) | CA2CA1CA12CA7CA9 | |
| SCHEMBL3770181 | 1.00 | CA2 (0.42) | CA2CA1CA12CA7CA9 | |
| SCHEMBL3734837 | 1.00 | CA2 (0.42) | CA2CA1CA12CA7CA9 | |
| SCHEMBL3774370 | 0.94 | CA2 (0.41) | CA2CA1CA12CA7CA9 | |
| SCHEMBL3774368 | 0.94 | CA2 (0.41) | CA2CA1CA12CA7CA9 | |
| SCHEMBL3774372 | 0.94 | CA2 (0.41) | CA2CA1CA12CA7CA9 | |
| SCHEMBL10180053 | 0.93 | CA2 (0.41) | CA2CA1CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829063-B2 | Development of molecular imaging probes for carbonic anhydrase-IX using click chemistry | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2010-11-09 | — | — | US | disclosed |