Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.68 |
| ▸ | NPC1 | O15118 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | CASP3 | P42574 | 1/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3805482 | 0.99 | RAB9A (0.67) | RAB9ANPC1MEN1KMT2ACASP3 | |
| SCHEMBL11921539 | 0.85 | RAB9A (0.61) | RAB9ANPC1MEN1KMT2ACASP3 | |
| SCHEMBL2972738 | 0.82 | CFTR (0.69) | RAB9ANPC1HRH3MAPTALDH1A1 | |
| SCHEMBL32319858 | 0.82 | RAB9A (1.00) | RAB9ANPC1MEN1KMT2ACASP3 | |
| SCHEMBL11903794 | 0.82 | RAB9A (1.00) | RAB9ANPC1MEN1KMT2ACASP3 | |
| SCHEMBL2974366 | 0.81 | CFTR (0.67) | RAB9ANPC1HRH3MAPTALDH1A1 | |
| SCHEMBL11924589 | 0.81 | RAB9A (0.81) | RAB9ANPC1MEN1KMT2ACASP3 | |
| SCHEMBL8487489 | 0.80 | RAB9A (0.79) | RAB9ANPC1MEN1KMT2ACASP3 | |
| SCHEMBL11924468 | 0.80 | RAB9A (0.79) | RAB9ANPC1MEN1KMT2ACASP3 | |
| SCHEMBL11924527 | 0.80 | RAB9A (0.79) | RAB9ANPC1MEN1KMT2ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139982-A1 | INDOLE DERIVATIVES FOR THE STIMULATION OF STEM CELL PROLIFERATION | THE UNIVERSITY OF SHEFFIELD (GB) | 2010-12-09 | — | — | WO | disclosed |