Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.72 |
| ▸ | NPC1 | O15118 | 4/20 | 0.72 |
| ▸ | CASP3 | P42574 | 1/20 | 0.72 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | IGF1R | P08069 | 3/20 | 0.52 |
| ▸ | MET | P08581 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13044605 | 0.92 | RAB9A (0.76) | RAB9ANPC1CASP3SENP7MEN1 | |
| SCHEMBL13042958 | 0.90 | RAB9A (0.72) | RAB9ANPC1CASP3SENP7MEN1 | |
| SCHEMBL13044620 | 0.85 | RAB9A (0.62) | RAB9ANPC1CASP3SENP7MEN1 | |
| SCHEMBL13043506 | 0.84 | RAB9A (0.71) | RAB9ANPC1CASP3SENP7MEN1 | |
| SCHEMBL11921534 | 0.84 | RAB9A (1.00) | RAB9ANPC1CASP3SENP7MEN1 | |
| SCHEMBL32319858 | 0.83 | RAB9A (1.00) | RAB9ANPC1CASP3SENP7MEN1 | |
| SCHEMBL11903794 | 0.83 | RAB9A (1.00) | RAB9ANPC1CASP3SENP7MEN1 | |
| SCHEMBL11921535 | 0.83 | RAB9A (0.74) | RAB9ANPC1CASP3SENP7MEN1 | |
| SCHEMBL13043017 | 0.80 | RAB9A (0.66) | RAB9ANPC1CASP3SENP7MEN1 | |
| SCHEMBL13044439 | 0.80 | NPC1 (0.64) | RAB9ANPC1CASP3SENP7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139982-A1 | INDOLE DERIVATIVES FOR THE STIMULATION OF STEM CELL PROLIFERATION | THE UNIVERSITY OF SHEFFIELD (GB) | 2010-12-09 | — | — | WO | disclosed |