SCHEMBL13045347

SCHEMBL13045347

C[C@@H](c1ccccc1)N(CC(=O)N(CCCCN)CC(=O)N(CC(=O)C(C)(C)C)[C@@H](C)c1ccccc1)C(=O)CN(CCCCNC(=N)N)C(=O)CN(CCCCN)C(=O)CN(CCCCN)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MC4R P32245 2/20 0.38
MC3R P41968 2/20 0.38
MC1R Q01726 1/20 0.38
NPY1R P25929 1/20 0.33
MC5R P33032 1/20 0.32
F2 P00734 1/20 0.30
F10 P00742 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10085139 0.92 MC4R (0.38) MC4RMC3RMC1RNPY1RMC5R
SCHEMBL10085153 0.91 MC3R (0.38) MC4RMC3RMC1RMC5RF2
SCHEMBL10085155 0.89 MC3R (0.38) MC4RMC3RMC1RMC5RF2
SCHEMBL12387503 0.82 MC3R (0.38) MC4RMC3RMC1RMC5RF2
SCHEMBL20388762 0.82 MC3R (0.58) MC4RMC3RMC1RNPY1RMC5R
SCHEMBL20388761 0.82 MC3R (0.58) MC4RMC3RMC1RNPY1RMC5R
SCHEMBL16315931 0.82 MC4R (0.42) MC4RMC3RMC1RNPY1RMC5R
SCHEMBL16299306 0.81 MC3R (0.39) MC4RMC3RMC1RNPY1RMC5R
SCHEMBL10085143 0.81 MC3R (0.38) MC4RMC3RMC1RMC5RF2
SCHEMBL20388657 0.78 MC4R (0.53) MC4RMC3RMC1RNPY1RMC5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7834144-B2 Prion-specific peptoid reagents NOVARTIS AG (CH) 2010-11-16 US disclosed
US-20070087972-A1 Prion-specific peptoid reagents NOVARTIS AG (CH) 2007-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070087972-A1 Prion-specific peptoid reagents PRNP, PARL, PCNP MC4R 3225/4885MC3R 3280/4885MC1R 3982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.