Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.69 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.67 |
| ▸ | FAAH | O00519 | 4/20 | 0.66 |
| ▸ | NAAA | Q02083 | 1/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.59 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21548098 | 0.96 | CASP2 (0.74) | CASP2DNM1FAAHNAAAEPHX2 | |
| SCHEMBL11132585 | 0.96 | CASP2 (0.74) | CASP2DNM1FAAHNAAAEPHX2 | |
| SCHEMBL12254784 | 0.96 | CASP2 (0.74) | CASP2DNM1FAAHNAAAEPHX2 | |
| SCHEMBL9230007 | 0.96 | CASP2 (0.74) | CASP2DNM1FAAHNAAAEPHX2 | |
| SCHEMBL965531 | 0.96 | CASP2 (0.74) | CASP2DNM1FAAHNAAAEPHX2 | |
| SCHEMBL20683710 | 0.96 | CASP2 (0.74) | CASP2DNM1FAAHNAAAEPHX2 | |
| SCHEMBL29290542 | 0.96 | CASP2 (0.74) | CASP2DNM1FAAHNAAAEPHX2 | |
| SCHEMBL11912070 | 0.94 | CASP2 (0.70) | CASP2DNM1FAAHNAAAEPHX2 | |
| SCHEMBL17670553 | 0.93 | CASP2 (0.69) | CASP2DNM1FAAHNAAAEPHX2 | |
| SCHEMBL11704010 | 0.91 | CASP2 (0.71) | CASP2DNM1FAAHNAAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834144-B2 | Prion-specific peptoid reagents | NOVARTIS AG (CH) | 2010-11-16 | — | — | US | disclosed |
| US-7834144-B2 | Prion-specific peptoid reagents | NOVARTIS AG (CH) | 2010-11-16 | — | — | US | disclosed |