Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305530 | 0.89 | PPARA (0.55) | EPHX1EPHX2MEN1KMT2ANPC1 | |
| SCHEMBL1305000 | 0.88 | MAPT (0.68) | MEN1KMT2ANPC1HTTLMNA | |
| SCHEMBL13945701 | 0.87 | EPHX2 (0.65) | EPHX1EPHX2MEN1KMT2ANPC1 | |
| SCHEMBL805971 | 0.87 | PPARA (0.61) | EPHX2MEN1KMT2ANPC1LMNA | |
| SCHEMBL16303954 | 0.87 | PPARA (0.61) | EPHX2MEN1KMT2ANPC1LMNA | |
| SCHEMBL9131125 | 0.87 | PPARA (0.52) | EPHX2MEN1KMT2ANPC1HTT | |
| SCHEMBL14345472 | 0.85 | PPARA (0.52) | EPHX1EPHX2MEN1KMT2ANPC1 | |
| SCHEMBL1306107 | 0.85 | PPARA (0.60) | EPHX2MEN1KMT2ANPC1HTT | |
| SCHEMBL9303663 | 0.85 | MEN1 (0.57) | EPHX1EPHX2MEN1KMT2ANPC1 | |
| SCHEMBL1305301 | 0.84 | MEN1 (0.66) | MEN1KMT2ANPC1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12065451-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2024-08-20 | — | — | US | claimed |
| US-8048896-B2 | Inhibit nonenzymatic formation of advanced glycation end-products (AGE) using e.g. aminoguanidine, OPB-9195 [(+/-)-2-isopropylidenehydrazono-4-oxo-thiazolidin-5-yla cetanilide], pyridoxamine, antioxidants, alagebrium, antihypertensives, angiotensin-converting enzyme inhibitors | Cell Viable Corporation (US) | 2011-11-01 | — | — | US | claimed |
| EP-1165064-B1 | NOVEL INHIBITORS OF FORMATION OF ADVANCED GLYCATION ENDPRODUCTS (AGE'S) | HOPE CITY (US) | 2004-02-25 | — | — | EP | claimed |
| US-6337350-B1 | CROSSLINKING INHIBITION OF PROTEINS | CITY OF HOPE | 2002-01-08 | — | — | US | claimed |
| EP-1165064-A2 | NOVEL INHIBITORS OF FORMATION OF ADVANCED GLYCATION ENDPRODUCTS (AGE'S) | City of Hope (US) | 2002-01-02 | — | — | EP | claimed |
| WO-2000059875-A2 | NOVEL INHIBITORS OF FORMATION OF ADVANCED GLYCATION ENDPRODUCTS (AGE'S) | CITY OF HOPE (US) | 2000-10-12 | — | — | WO | claimed |
| US-5268500-A | Aromatic urea carboxylated compound | MONTEFIORE MEDICAL CENTER (US) | 1993-12-07 | — | — | US | claimed |
| EP-0358724-A4 | COMPOUND, COMPOSITION AND METHOD FOR THE REDUCTION OF LIPIDS THE MODIFICATION OF THE AFFINITY OF HEMOGLOBIN FOR OXYGEN AND THE PREVENTION OF PLATELET AGGREGATION. | LALEZARI IRAJ (US) | 1990-06-05 | — | — | EP | claimed |
| EP-0358724-A1 | COMPOUND, COMPOSITION AND METHOD FOR THE REDUCTION OF LIPIDS THE MODIFICATION OF THE AFFINITY OF HEMOGLOBIN FOR OXYGEN AND THE PREVENTION OF PLATELET AGGREGATION | LALEZARI, Iraj (US) | 1990-03-21 | — | — | EP | claimed |
| WO-1988010113-A1 | COMPOUND, COMPOSITION AND METHOD FOR THE REDUCTION OF LIPIDS THE MODIFICATION OF THE AFFINITY OF HEMOGLOBIN FOR OXYGEN AND THE PREVENTION OF PLATELET AGGREGATION | LALEZARI IRAJ (US) | 1988-12-29 | — | — | WO | claimed |
| US-12065451-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2024-08-20 | — | — | US | disclosed |
| CN-218899918-U | Portable micro-nano atomizing eye patch | 广东多美达智能终端有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-114630910-A | Improved homology-dependent repair genome editing | 伊纳瑞农业技术有限公司 | 2022-06-14 | — | — | CN | disclosed |
| US-20220056062-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2022-02-24 | — | — | US | disclosed |
| US-8053449-B2 | Method for inhibiting AGE complex formation | Cell Viable Corporation (US) | 2011-11-08 | — | — | US | disclosed |
| US-5093367-A | Arylureidophenoxymethylpropionic acids which have activity in dissociation of oxygen from hemoglobin | MONTEFIORE MEDICAL CENTER (US) | 1992-03-03 | — | — | US | disclosed |
| EP-0420930-A4 | METHOD OF SYNTHESIS AND NOVEL COMPOUNDS FOR PHARMACEUTICAL USES | — | 1991-12-04 | — | — | EP | disclosed |
| EP-0420930-A1 | METHOD OF SYNTHESIS AND NOVEL COMPOUNDS FOR PHARMACEUTICAL USES | LALEZARI, Iraj (US) | 1991-04-10 | — | — | EP | disclosed |
| US-4921997-A | Method of synthesis and novel compounds for pharmaceutical uses | MONTEFIORE MEDICAL CENTER (US) | 1990-05-01 | — | — | US | disclosed |
| WO-1989012622-A1 | METHOD OF SYNTHESIS AND NOVEL COMPOUNDS FOR PHARMACEUTICAL USES | LALEZARI IRAJ (US) | 1989-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220056062-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OSBP, OCIAD2, OCIAD1 | EPHX1 1495/4885EPHX2 2411/4885MEN1 1082/4885 |
| US-12065451-B2 | Organic electroluminescent materials and devices | OSBP, OCIAD2, OCIAD1 | EPHX1 1495/4885EPHX2 2411/4885MEN1 1082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.