Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | PPARA | Q07869 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | GRIK1 | P39086 | 9/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | FABP2 | P12104 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303086 | 0.90 | MAPT (0.57) | MEN1KMT2AMAPTPPARACYP1A2 | |
| SCHEMBL9131125 | 0.88 | PPARA (0.52) | MEN1KMT2AMAPTPPARACYP1A2 | |
| SCHEMBL1306107 | 0.86 | PPARA (0.60) | MEN1KMT2AMAPTPPARACYP1A2 | |
| SCHEMBL9561356 | 0.85 | MAPT (0.67) | MEN1KMT2AMAPTPPARACYP1A2 | |
| SCHEMBL1305530 | 0.85 | PPARA (0.55) | MEN1KMT2AMAPTPPARACYP1A2 | |
| SCHEMBL1304565 | 0.85 | EPHX1 (0.59) | MEN1KMT2AMAPTPPARACYP1A2 | |
| SCHEMBL1304985 | 0.84 | CA12 (0.60) | MEN1KMT2AMAPTCA12CA1 | |
| SCHEMBL806016 | 0.83 | PPARA (0.50) | MEN1KMT2AMAPTPPARACYP1A2 | |
| SCHEMBL16303954 | 0.83 | PPARA (0.61) | MEN1KMT2AMAPTPPARACYP1A2 | |
| SCHEMBL805971 | 0.83 | PPARA (0.61) | MEN1KMT2AMAPTPPARACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292935-A | Carboxyalkoxy-substituted diphenylurea | MONTEFIORE MEDICAL CENTER (US) | 1994-03-08 | — | — | US | disclosed |
| US-5093367-A | Arylureidophenoxymethylpropionic acids which have activity in dissociation of oxygen from hemoglobin | MONTEFIORE MEDICAL CENTER (US) | 1992-03-03 | — | — | US | disclosed |
| EP-0420930-A4 | METHOD OF SYNTHESIS AND NOVEL COMPOUNDS FOR PHARMACEUTICAL USES | — | 1991-12-04 | — | — | EP | disclosed |
| EP-0420930-A1 | METHOD OF SYNTHESIS AND NOVEL COMPOUNDS FOR PHARMACEUTICAL USES | LALEZARI, Iraj (US) | 1991-04-10 | — | — | EP | disclosed |
| US-4921997-A | Method of synthesis and novel compounds for pharmaceutical uses | MONTEFIORE MEDICAL CENTER (US) | 1990-05-01 | — | — | US | disclosed |
| WO-1989012622-A1 | METHOD OF SYNTHESIS AND NOVEL COMPOUNDS FOR PHARMACEUTICAL USES | LALEZARI IRAJ (US) | 1989-12-28 | — | — | WO | disclosed |