Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2622097 | 0.94 | CTSL (0.40) | CTSLHTR2CSLC6A4CCR5CTSB | |
| SCHEMBL2113432 | 0.94 | CTSL (0.40) | CTSLHTR2CSLC6A4CCR5CTSB | |
| SCHEMBL2622149 | 0.93 | HSD17B10 (0.39) | CTSLHTR2CSLC6A4CCR5CTSB | |
| SCHEMBL2117031 | 0.93 | HSD17B10 (0.39) | CTSLHTR2CSLC6A4CCR5CTSB | |
| SCHEMBL2439991 | 0.90 | CTSL (0.42) | CTSLHTR2CSLC6A4CCR5L3MBTL1 | |
| SCHEMBL12299754 | 0.90 | CTSL (0.42) | CTSLHTR2CSLC6A4CCR5L3MBTL1 | |
| SCHEMBL17577847 | 0.90 | CTSL (0.38) | CTSLHTR2CSLC6A4CCR5CTSB | |
| SCHEMBL13049917 | 0.87 | CTSL (0.51) | CTSLAGTR2MAPK1 | |
| SCHEMBL23441259 | 0.83 | CTSL (0.44) | CTSLHTR2CSLC6A4CTSBCTSS | |
| SCHEMBL23441258 | 0.83 | CTSL (0.44) | CTSLHTR2CSLC6A4CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138496-A1 | IAP INHIBITORS | TETRALOGIC PHARMACEUTICALS CORP. (US) | 2010-12-02 | — | — | WO | disclosed |