Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 9/20 | 0.43 |
| ▸ | CA9 | Q16790 | 7/20 | 0.43 |
| ▸ | CA12 | O43570 | 7/20 | 0.43 |
| ▸ | CA1 | P00915 | 7/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1371517 | 1.00 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL13542061 | 1.00 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL1371518 | 1.00 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL14031258 | 1.00 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL13029576 | 1.00 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL6272209 | 0.86 | CYP2D6 (0.56) | MAPTCYP2D6THRBHSD17B10CA2 | |
| SCHEMBL14019274 | 0.86 | CYP2D6 (0.56) | MAPTCYP2D6THRBHSD17B10CA2 | |
| SCHEMBL5570985 | 0.86 | CYP2D6 (0.56) | MAPTCYP2D6THRBHSD17B10CA2 | |
| SCHEMBL17969688 | 0.86 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL17230115 | 0.84 | POLB (0.54) | LMNAKMT2APOLBALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834159-B2 | Pharmacokinetics; glycosyltransferases; vaccines | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-11-16 | — | — | US | disclosed |
| US-20100009425-A1 | Glycoprotein synthesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-01-14 | — | — | US | disclosed |
| US-20080064059-A1 | In Vivo Site-Specific Incorporation of N-Acetyl-Galactosamine Amino Acids in Eubacteria | SCRIPPS RESEARCH INSTITUTE | 2008-03-13 | — | — | US | disclosed |
| US-7262040-B2 | Glycoprotein synthesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-08-28 | — | — | US | disclosed |
| US-20070172915-A1 | Glycoprotein synthesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-07-26 | — | — | US | disclosed |
| US-7183082-B2 | Glycoprotein synthesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-02-27 | — | — | US | disclosed |