Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13049917 | 0.89 | CTSL (0.51) | CTSLITGB3ITGA2BELANEMAPK1 | |
| SCHEMBL17577890 | 0.88 | CTSL (0.51) | CTSLITGB3ITGA2BELANEMAPK1 | |
| SCHEMBL17577847 | 0.88 | CTSL (0.38) | CTSLELANE | |
| SCHEMBL12299752 | 0.87 | CTSL (0.57) | CTSLITGB3ITGA2BELANE | |
| SCHEMBL2441255 | 0.87 | CTSL (0.57) | CTSLITGB3ITGA2BELANE | |
| SCHEMBL2115422 | 0.87 | CTSL (0.52) | CTSLITGB3ITGA2BELANEMAPK1 | |
| SCHEMBL2622093 | 0.87 | CTSL (0.52) | CTSLITGB3ITGA2BELANEMAPK1 | |
| SCHEMBL2115417 | 0.86 | CTSL (0.49) | CTSLITGB3ITGA2BCMA1MAPK1 | |
| SCHEMBL2622146 | 0.86 | CTSL (0.49) | CTSLITGB3ITGA2BCMA1MAPK1 | |
| SCHEMBL17577895 | 0.86 | CTSL (0.49) | CTSLITGB3ITGA2BCMA1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138496-A1 | IAP INHIBITORS | TETRALOGIC PHARMACEUTICALS CORP. (US) | 2010-12-02 | — | — | WO | disclosed |