Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.43 |
| ▸ | F2 | P00734 | 10/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | TMPRSS11D | O60235 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345195 | 0.90 | F2 (0.49) | F10F2PRSS1TMPRSS11DPLG | |
| SCHEMBL15080624 | 0.87 | F10 (0.42) | F10F2TPSAB1PRSS1TPSD1 | |
| SCHEMBL8346530 | 0.82 | F2 (0.57) | F10F2PRSS1TMPRSS11DPLG | |
| SCHEMBL8345186 | 0.82 | F2 (0.51) | F10F2PRSS1TMPRSS11DPLG | |
| SCHEMBL13456454 | 0.79 | F10 (0.54) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8344650 | 0.78 | F2 (0.56) | F10F2PRSS1TMPRSS11DPLG | |
| SCHEMBL8353843 | 0.77 | F2 (0.43) | F10F2PRSS1TMPRSS11DPLG | |
| SCHEMBL14628420 | 0.77 | F10 (0.49) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL308289 | 0.77 | F10 (0.49) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL13283064 | 0.76 | CA12 (0.47) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838560-B2 | for the therapy, prophylaxis and diagnosis of a tumor; benzylsulfonyl-D-Ser-Glu-4-amidinobenzylamidexTFA | THE MEDICINES COMPANY (LEIPZIG) GMBH (DE) | 2010-11-23 | — | — | US | disclosed |