Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.60 |
| ▸ | STAT3 | P40763 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KIF11 | P52732 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12984288 | 0.92 | LMNA (0.59) | LMNASTAT3MAPTKIF11POLB | |
| SCHEMBL13725813 | 0.88 | LMNA (0.54) | LMNASTAT3MAPTKIF11ABCG2 | |
| SCHEMBL16299546 | 0.85 | MAPT (0.48) | LMNASTAT3MAPTKIF11ABCG2 | |
| SCHEMBL10085945 | 0.82 | MAPT (0.65) | LMNAMAPTKIF11POLBABCG2 | |
| SCHEMBL8403110 | 0.81 | MAPT (0.67) | LMNAMAPTKIF11ABCG2TP53 | |
| SCHEMBL764244 | 0.80 | LMNA (0.52) | LMNASTAT3MAPTKIF11POLB | |
| SCHEMBL11912475 | 0.80 | ABCG2 (0.54) | LMNASTAT3MAPTKIF11ABCG2 | |
| SCHEMBL764226 | 0.80 | LMNA (0.51) | LMNASTAT3MAPTKIF11POLB | |
| SCHEMBL8404029 | 0.79 | LMNA (0.51) | LMNASTAT3MAPTKIF11POLB | |
| SCHEMBL11912456 | 0.79 | LMNA (0.52) | LMNASTAT3MAPTKIF11ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138706-A1 | METHODS FOR TREATING BREAST CANCER | PTC THERAPEUTICS, INC. (US) | 2010-12-02 | — | — | WO | disclosed |