Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | OGG1 | O15527 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11982037 | 0.82 | — | — | |
| SCHEMBL3842531 | 0.82 | LMNA (0.73) | LMNAMAPTMEN1MAPK1KMT2A | |
| SCHEMBL9126141 | 0.82 | LMNA (0.73) | LMNAMAPTMEN1MAPK1KMT2A | |
| SCHEMBL132367 | 0.82 | LMNA (0.73) | LMNAMAPTMEN1MAPK1KMT2A | |
| SCHEMBL29984922 | 0.79 | LMNA (0.70) | LMNAMAPTMEN1MAPK1KMT2A | |
| Ethylene SCHEMBL10490014 | 0.77 | LMNA (0.67) | LMNAMAPTMEN1MAPK1KMT2A | |
| SCHEMBL870184 | 0.76 | LMNA (0.76) | LMNAMAPTMEN1MAPK1KMT2A | |
| SCHEMBL9355961 | 0.75 | LMNA (0.64) | LMNAMAPTMEN1MAPK1KMT2A | |
| SCHEMBL3910627 | 0.75 | LMNA (0.64) | LMNAMAPTMEN1MAPK1KMT2A | |
| SCHEMBL10629625 | 0.75 | LMNA (0.64) | LMNAMAPTMEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136111-A1 | COMPOSITION, CONTAINING AT LEAST ONE EMITTER COMPOUND AND AT LEAST ONE POLYMER WITH CONJUGATION-INTERRUPTING UNITS | MERCK PATENT GMBH (DE) | 2010-12-02 | — | — | WO | disclosed |