SCHEMBL13052178

SCHEMBL13052178

O=C(Nc1ccccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12)c1ccc2ccccc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 3/20 0.55
MEN1 O00255 2/20 0.55
POLB P06746 2/20 0.55
KMT2A Q03164 2/20 0.55
ATM Q13315 1/20 0.55
PLEC Q15149 1/20 0.55
CA9 Q16790 7/20 0.50
L3MBTL1 Q9Y468 1/20 0.49
ALPL P05186 1/20 0.46
ALPI P09923 1/20 0.46
ALPG P10696 1/20 0.46
DNASE1L3 Q13609 1/20 0.45
PRMT1 Q99873 1/20 0.45
CA1 P00915 6/20 0.44
CA2 P00918 6/20 0.44
CA12 O43570 1/20 0.44
DEGS1 O15121 1/20 0.43
TP53 P04637 1/20 0.43
GPR35 Q9HC97 1/20 0.43
GPR55 Q9Y2T6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13052174 0.89 USP2 (0.64) USP2MEN1POLBKMT2AATM
SCHEMBL17089150 0.80 USP2 (0.53) USP2MEN1POLBKMT2AATM
SCHEMBL21760911 0.76 MEN1 (0.71) USP2MEN1POLBKMT2AATM
SCHEMBL8930410 0.76 MEN1 (0.74) USP2MEN1POLBKMT2AATM
SCHEMBL14193707 0.75 USP2 (0.63) USP2MEN1POLBKMT2AATM
SCHEMBL107875 0.74 USP2 (0.76) USP2MEN1POLBKMT2AATM
SCHEMBL29781098 0.74 USP2 (0.76) USP2MEN1POLBKMT2AATM
SCHEMBL29591827 0.74 USP2 (0.76) USP2MEN1POLBKMT2AATM
SCHEMBL16169467 0.74 MEN1 (0.68) USP2MEN1POLBKMT2AATM
SCHEMBL8335663 0.74 NPC1 (0.71) MEN1KMT2ADEGS1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8309319-B2 Fluorescent probe for measurement of UDP-glucuronosyltransferase THE UNIVERSITY OF TOKYO (JP) 2012-11-13 US disclosed
US-8309319-B2 Fluorescent probe for measurement of UDP-glucuronosyltransferase THE UNIVERSITY OF TOKYO (JP) 2012-11-13 US disclosed
US-20100297681-A1 FLUORESCENT PROBE FOR MEASUREMENT OF GLUCURONATE TRANSFERASE THE UNIVERSITY OF TOKYO (JP) 2010-11-25 US disclosed
US-20100297681-A1 FLUORESCENT PROBE FOR MEASUREMENT OF GLUCURONATE TRANSFERASE THE UNIVERSITY OF TOKYO (JP) 2010-11-25 US disclosed