Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13775112 | 0.80 | CYP3A4 (0.68) | CYP3A4GAANPSR1ADORA2BALDH1A1 | |
| SCHEMBL713076 | 0.80 | CYP3A4 (0.76) | CYP3A4GAANPSR1ADORA2BALDH1A1 | |
| SCHEMBL24495805 | 0.78 | CYP3A4 (0.55) | CYP3A4GAANPSR1ADORA2BALDH1A1 | |
| SCHEMBL25588847 | 0.76 | CYP3A4 (0.48) | CYP3A4GAANPSR1ADORA2BALDH1A1 | |
| SCHEMBL14037107 | 0.75 | ADORA2B (0.32) | ADORA2B | |
| SCHEMBL24118573 | 0.74 | CYP3A4 (0.67) | CYP3A4GAANPSR1ADORA2BALDH1A1 | |
| SCHEMBL19498758 | 0.74 | CYP3A4 (0.67) | CYP3A4GAANPSR1ADORA2BUSP2 | |
| SCHEMBL15946190 | 0.74 | CYP3A4 (0.50) | CYP3A4GAANPSR1ADORA2BALDH1A1 | |
| SCHEMBL12999576 | 0.73 | CYP3A4 (0.48) | CYP3A4GAANPSR1ADORA2BALDH1A1 | |
| SCHEMBL16864614 | 0.73 | CYP3A4 (0.64) | CYP3A4GAANPSR1ADORA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100304305-A1 | RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING POLYMER HAVING NITROGEN-CONTAINING SILYL GROUP | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-12-02 | — | — | US | disclosed |