Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13053369 | 0.79 | — | — | |
| SCHEMBL30565480 | 0.78 | STAT3 (0.39) | STAT3ALDH1A1POLBTP53ENPP3 | |
| SCHEMBL20014121 | 0.78 | STAT3 (0.39) | STAT3ALDH1A1POLBTP53ENPP3 | |
| SCHEMBL15197306 | 0.75 | ALDH1A1 (0.35) | STAT3ALDH1A1POLBTP53ENPP3 | |
| SCHEMBL20569464 | 0.74 | SMN1; SMN2 (0.39) | STAT3ALDH1A1POLBTP53ENPP3 | |
| SCHEMBL15197303 | 0.74 | CYP2D6 (0.34) | STAT3ALDH1A1KMT2ACYP2C9CYP3A4 | |
| SCHEMBL21987509 | 0.73 | STAT3 (0.41) | STAT3ALDH1A1POLBTP53ENPP3 | |
| SCHEMBL21987513 | 0.73 | STAT3 (0.41) | STAT3ALDH1A1POLBTP53ENPP3 | |
| SCHEMBL15197307 | 0.73 | CYP2D6 (0.34) | STAT3ALDH1A1ENPP3ENPP1ENPP2 | |
| SCHEMBL20014131 | 0.73 | KMT2A (0.40) | STAT3ALDH1A1POLBTP53ENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7837982-B2 | Imaging agents | EMORY UNIVERSITY (US) | 2010-11-23 | — | — | US | disclosed |
| US-20070082879-A1 | Imaging Agents | EMORY UNIVERSITY (US) | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082879-A1 | Imaging Agents | SLC7A1, SSTR1, SSTR3 | STAT3 3976/4885ALDH1A1 3166/4885POLB 1552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.