Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 9/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30263006 | 0.82 | KDM4E (0.61) | KMT2AMEN1LCKSMN1; SMN2 | |
| SCHEMBL24104137 | 0.81 | KMT2A (0.64) | RAB9AMAPTKMT2AMEN1LCK | |
| SCHEMBL10600068 | 0.81 | RAB9A (0.81) | RAB9AMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL17090573 | 0.81 | LCK (0.69) | RAB9AMAPTKMT2AMEN1LCK | |
| SCHEMBL2666847 | 0.81 | DYRK1A (0.67) | RAB9ALCK | |
| SCHEMBL29506738 | 0.81 | LCK (0.69) | RAB9AMAPTKMT2AMEN1LCK | |
| SCHEMBL31452315 | 0.80 | RAB9A (0.45) | RAB9AMAPTKMT2AMEN1LCK | |
| SCHEMBL3943412 | 0.80 | LCK (0.61) | RAB9AKMT2AMEN1LCKSMN1; SMN2 | |
| SCHEMBL10118217 | 0.80 | RAB9A (0.76) | RAB9ALCK | |
| SCHEMBL30263005 | 0.80 | LCK (0.61) | RAB9AKMT2AMEN1LCKSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838543-B2 | Melanin Concentrating Hormone Receptor 1; Obesity; 4'-Fluoro-biphenyl-4-carboxylic acid {2-[(2-dimethylamino-ethyl)-methyl-amino]-benzothiazol-6-yl}amide; 4-Cyclohexyl-N-{2-[(2-dimethylamino-ethyl)-methyl-amino]-benzooxazol-5-yl}-benzamide; 2-aminobenzoxazoles or 2-aminobenzothiazoles | ELI LILLY AND COMPANY (US) | 2010-11-23 | — | — | US | disclosed |