SCHEMBL13054822

SCHEMBL13054822

COCOc1ccc(C(C)(C)c2ccc(OC)c(C3CCCCC3)c2)cc1C1CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 13/20 0.47
PTGDR Q13258 6/20 0.42
HTR2A P28223 3/20 0.39
PTGER2 P43116 1/20 0.39
CNR2 P34972 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL347064 0.79 PTGDR2 (0.52) PTGDR2PTGDRPTGER2
SCHEMBL29480885 0.79 PTGDR2 (0.52) PTGDR2PTGDRPTGER2
SCHEMBL12438735 0.79 PTGDR2 (0.46) PTGDR2PTGDRPTGER2
SCHEMBL13054808 0.78 PTGDR2 (0.44) PTGDR2PTGDRHTR2APTGER2
SCHEMBL18210670 0.74 PTGDR2 (0.52) PTGDR2PTGDRPTGER2ALDH1A1
SCHEMBL17826406 0.73 PTGDR2 (0.44) PTGDR2PTGDRCNR2KDM4EALDH1A1
SCHEMBL13054812 0.73 KDM4E (0.43) KDM4EALDH1A1
SCHEMBL10961850 0.73 DDB1 (0.46) ALDH1A1
SCHEMBL31019754 0.72 PDE4A (0.47) ALDH1A1
SCHEMBL13054821 0.71 CYP2C19 (0.46) KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8808951-B2 Electrophotographic photosensitive body HODOGAYA CHEMICAL CO., LTD. (JP) 2014-08-19 US disclosed
US-20130266343-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY HODOGAYA CHEMICAL CO LTD (JP) 2013-10-10 US disclosed
US-20100291480-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY HODOGAYA CHEMICAL CO., LTD. (JP) 2010-11-18 US disclosed
US-7790342-B2 Electrophotographic photosensitive body HODOGAYA CHEMICAL CO., LTD. (JP) 2010-09-07 US disclosed
US-20090226830-A1 Using in combination a p-terphenyl compound, N-N'-diphenyl-N,N'-di-p- tolyl-4,4''-diamino-p-terphenyl, as charge transport agent and a polycarbonate homo- and copolymer of bisphenol A or analogues as binder; providing an high photosensitive, improved residual potential and high durability HODOGAYA CHEMICAL CO., LTD. (JP) 2009-09-10 US disclosed