SCHEMBL12438735

SCHEMBL12438735

COc1ccc(C(C)(C)c2ccc(OC(C)=O)c(C3CCCCC3)c2)cc1C1CCCCC1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 11/20 0.46
NR3C1 P04150 1/20 0.42
PTGDR Q13258 5/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TSHR P16473 1/20 0.39
JUN P05412 1/20 0.39
NFKB1 P19838 1/20 0.39
PTGER2 P43116 1/20 0.38
PTGS1 P23219 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2691780 0.88 PTGDR2 (0.45) PTGDR2PTGDRMEN1KMT2ATSHR
SCHEMBL14173151 0.84 PTGDR2 (0.47) PTGDR2PTGDRPTGER2
SCHEMBL14173089 0.80 PTGDR2 (0.46) PTGDR2PTGDRMEN1KMT2APTGER2
SCHEMBL14173144 0.79 PTGDR2 (0.43) PTGDR2PTGDRKMT2APTGER2
SCHEMBL13054822 0.79 PTGDR2 (0.47) PTGDR2PTGDRPTGER2
SCHEMBL12438745 0.78 PTGDR2 (0.43) PTGDR2NR3C1PTGDRMEN1KMT2A
SCHEMBL4883830 0.77 PTGDR2 (0.64) PTGDR2PTGDRPTGER2
SCHEMBL9479024 0.77 PTGDR2 (0.54) PTGDR2PTGDRPTGER2
SCHEMBL14173084 0.76 PTGDR2 (0.43) PTGDR2PTGDRMEN1KMT2APTGER2
SCHEMBL13864939 0.76 PTGDR2 (0.41) PTGDR2PTGDRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8396399-B2 Toner bearing member, developing device, image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2013-03-12 US disclosed
US-20130040234-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, MANUFACTURING METHOD THEREFOR AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2013-02-14 US disclosed
US-8369755-B2 Developing device and image forming apparatus using the developing device RICOH COMPANY, LTD. (JP) 2013-02-05 US disclosed
US-20110176835-A1 TONER BEARING MEMBER, DEVELOPMENT DEVICE, AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD (JP) 2011-07-21 US disclosed
US-20100329748-A1 DEVELOPING DEVICE AND IMAGE FORMING APPARATUS USING THE DEVELOPING DEVICE RICOH COMPANY, LTD. (JP) 2010-12-30 US disclosed
US-20100303509-A1 Toner Bearing Member, Developing Device, Image Forming Apparatus, And Image Forming Method RICOH COMPANY, LTD. (JP) 2010-12-02 US disclosed
US-20080146759-A1 Sulfur-Containing Compound, Method for Producing Same, Sulfur-Containing Polymer, and Optical Material IDEMITSU KOSAN CO., LTD (JP) 2008-06-19 US disclosed