Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GLS | O94925 | 3/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14877950 | 0.93 | KDM4A (0.47) | KDM4AL3MBTL1GLSNAMPTGAA | |
| SCHEMBL22702218 | 0.93 | KDM4A (0.47) | KDM4AL3MBTL1GLSNAMPTGAA | |
| SCHEMBL27113191 | 0.91 | KDM4A (0.46) | KDM4AL3MBTL1GLSNAMPTGAA | |
| SCHEMBL29402185 | 0.91 | KDM4A (0.46) | KDM4AL3MBTL1GLSNAMPTGAA | |
| SCHEMBL22702229 | 0.91 | KDM4A (0.46) | KDM4AL3MBTL1GLSNAMPTGAA | |
| SCHEMBL626784 | 0.91 | GAA (0.52) | KDM4AL3MBTL1GLSNAMPTGAA | |
| SCHEMBL27840005 | 0.91 | KDM4A (0.46) | KDM4AL3MBTL1GLSNAMPTGAA | |
| SCHEMBL15861836 | 0.90 | HDAC1 (0.46) | KDM4AL3MBTL1GLSNAMPTGAA | |
| SCHEMBL4145619 | 0.89 | KDM4A (0.47) | KDM4AL3MBTL1GLSNAMPTGAA | |
| SCHEMBL7540531 | 0.89 | GAA (0.47) | KDM4AL3MBTL1GLSNAMPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365514-A1 | MACROCYCLIC COMPOUNDS | NOVO NORDISK RESEARCH CENTRE OXFORD LIMITED (GB) | 2023-11-16 | — | — | US | disclosed |
| US-20200399232-A1 | MACROCYCLIC COMPOUNDS | ZIYLO LTD (GB) | 2020-12-24 | — | — | US | disclosed |
| US-10800747-B2 | Macrocyclic compounds | ZIYLO LTD (GB) | 2020-10-13 | — | — | US | disclosed |
| US-8426105-B2 | Resist-modifying composition and pattern forming process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-04-23 | — | — | US | disclosed |
| US-8426105-B2 | Resist-modifying composition and pattern forming process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-04-23 | — | — | US | disclosed |
| US-20100297554-A1 | RESIST-MODIFYING COMPOSITION AND PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10800747-B2 | Macrocyclic compounds | SLC2A4, GALE, MPI | KDM4A 3374/4885L3MBTL1 4739/4885GLS 1385/4885 |
| US-20200399232-A1 | MACROCYCLIC COMPOUNDS | SLC2A4, GALE, MPI | KDM4A 3374/4885L3MBTL1 4739/4885GLS 1385/4885 |
| US-20230365514-A1 | MACROCYCLIC COMPOUNDS | SLC2A4, GALE, MPI | KDM4A 3374/4885L3MBTL1 4739/4885GLS 1385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.