SCHEMBL14877950

SCHEMBL14877950

CCc1cc(CNC(=O)OC(C)(C)C)cc(CNC(=O)OC(C)(C)C)c1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4A O75164 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
GLS O94925 3/20 0.44
NAMPT P43490 2/20 0.44
GAA P10253 1/20 0.43
HDAC1 Q13547 1/20 0.43
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CTSK P43235 1/20 0.40
SYK P43405 1/20 0.40
CA12 O43570 1/20 0.40
CA7 P43166 1/20 0.40
CA14 Q9ULX7 1/20 0.40
SERPINE1 P05121 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13055397 0.93 KDM4A (0.51) KDM4AL3MBTL1GLSNAMPTGAA
SCHEMBL13981921 0.87 GLS (0.55) KDM4AL3MBTL1GLSNAMPTHDAC1
SCHEMBL22702218 0.86 KDM4A (0.47) KDM4AL3MBTL1GLSNAMPTGAA
SCHEMBL8372079 0.86 L3MBTL1 (0.56) KDM4AL3MBTL1NAMPTGAAHDAC1
SCHEMBL24139848 0.86 DYRK1A (0.50) KDM4AL3MBTL1GLSNAMPTGAA
SCHEMBL22702229 0.85 KDM4A (0.46) KDM4AL3MBTL1GLSNAMPTGAA
SCHEMBL29402185 0.85 KDM4A (0.46) KDM4AL3MBTL1GLSNAMPTGAA
SCHEMBL626784 0.85 GAA (0.52) KDM4AL3MBTL1GLSNAMPTGAA
SCHEMBL27840005 0.85 KDM4A (0.46) KDM4AL3MBTL1GLSNAMPTGAA
SCHEMBL27113191 0.85 KDM4A (0.46) KDM4AL3MBTL1GLSNAMPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426105-B2 Resist-modifying composition and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-04-23 US disclosed