Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | EEF2K | O00418 | 1/20 | 0.30 |
| ▸ | PLK4 | O00444 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | EEF2 | P13639 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ITK | Q08881 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1223457 | 0.97 | CA1 (0.33) | CA1CA2 | |
| Bicarbonate SCHEMBL28771598 | 0.93 | CA1 (0.33) | CA1CA2MEN1EEF2KPLK4 | |
| Acetic Acid SCHEMBL28811876 | 0.85 | CA1 (0.39) | CA1CA2MEN1EEF2KPLK4 | |
| Acetic Acid SCHEMBL15392706 | 0.82 | CA1 (0.47) | CA1CA2MEN1EEF2KPLK4 | |
| Bromide SCHEMBL710393 | 0.82 | CA1 (0.39) | CA1CA2MEN1EEF2KPLK4 | |
| Phthalic Acid SCHEMBL21378208 | 0.81 | ALDH1A1 (0.35) | CA1CA2MEN1EEF2KPLK4 | |
| Sulfuric Acid SCHEMBL17102575 | 0.81 | CA1 (0.33) | CA1CA2 | |
| Phosphoric Acid SCHEMBL25379987 | 0.81 | CTDSP1 (0.37) | CA1CA2MEN1EEF2KPLK4 | |
| Acetic Acid SCHEMBL2788542 | 0.80 | CA1 (0.55) | CA1CA2MEN1EEF2KPLK4 | |
| Phthalic Acid SCHEMBL28390383 | 0.80 | ALDH1A1 (0.42) | CA1CA2MEN1EEF2KPLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2158248-B1 | CATALYST FOR CURING EPOXIDES | BASF SE (DE) | 2012-08-15 | — | — | EP | claimed |
| US-8053546-B2 | Catalyst for curing epoxides | BASF SE (DE) | 2011-11-08 | — | — | US | claimed |
| US-20100187715-A1 | CATALYST FOR CURING EPOXIDES | BASF SE (DE) | 2010-07-29 | — | — | US | claimed |
| EP-0458502-B1 | Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom | DOW GLOBAL TECHNOLOGIES INC (US) | 2003-06-18 | — | — | EP | claimed |
| US-5169473-A | Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability | THE DOW CHEMICAL COMPANY (US) | 1992-12-08 | — | — | US | claimed |
| EP-0458502-A2 | Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom | THE DOW CHEMICAL COMPANY (US) | 1991-11-27 | — | — | EP | claimed |
| US-20120259044-A1 | HYPERBRANCHED POLYMERS FOR MODIFYING THE TOUGHNESS OF ANIONICALLY CURED EPOXY RESIN SYSTEMS | BASF SE (DE) | 2012-10-11 | — | — | US | disclosed |
| US-8247517-B2 | Catalyst for curing epoxides | BASF SE (DE) | 2012-08-21 | — | — | US | disclosed |
| US-8202580-B2 | Catalyst for curing epoxides | BASF SE (DE) | 2012-06-19 | — | — | US | disclosed |
| US-8193297-B2 | Catalyst for curing epoxides | BASF SE (DE) | 2012-06-05 | — | — | US | disclosed |
| US-8053546-B2 | Catalyst for curing epoxides | BASF SE (DE) | 2011-11-08 | — | — | US | disclosed |
| US-8053546-B2 | Catalyst for curing epoxides | BASF SE (DE) | 2011-11-08 | — | — | US | disclosed |
| US-20100187715-A1 | CATALYST FOR CURING EPOXIDES | BASF SE (DE) | 2010-07-29 | — | — | US | disclosed |
| US-5342865-A | Solvent system | THE DOW CHEMICAL COMPANY (US) | 1994-08-30 | — | — | US | disclosed |
| EP-0567248-A1 | Solvent system | THE DOW CHEMICAL COMPANY (US) | 1993-10-27 | — | — | EP | disclosed |
| EP-0553887-A2 | Catalysts and epoxy resin composition containing the same | THE DOW CHEMICAL COMPANY (US) | 1993-08-04 | — | — | EP | disclosed |
| US-5169473-A | Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability | THE DOW CHEMICAL COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| EP-0458502-A2 | Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom | THE DOW CHEMICAL COMPANY (US) | 1991-11-27 | — | — | EP | disclosed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | disclosed |
| EP-0328020-A2 | Use of a catalyst in epoxy compositions | THE DOW CHEMICAL COMPANY (US) | 1989-08-16 | — | — | EP | disclosed |