SCHEMBL1305658

SCHEMBL1305658

CCC/C=C(/C/C=C(\C)CCC=C(C)C)CCC

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.52
SQLE Q14534 6/20 0.50
MEN1 O00255 2/20 0.48
CYP3A4 P08684 2/20 0.48
ALOX15 P16050 2/20 0.48
MAPT P10636 2/20 0.47
ALDH1A1 P00352 1/20 0.47
UGT1A1 P22309 1/20 0.47
FNTA P49354 3/20 0.45
FNTB P49356 3/20 0.45
KDM4E B2RXH2 1/20 0.43
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1305660 1.00 KMT2A (0.52) KMT2ASQLEMEN1CYP3A4ALOX15
SCHEMBL27499250 0.86 SQLE (0.36) KMT2ASQLEMEN1CYP3A4ALOX15
SCHEMBL6631251 0.82 KMT2A (0.76) KMT2ASQLEMEN1CYP3A4ALOX15
SCHEMBL5593549 0.82 KMT2A (0.76) KMT2ASQLEMEN1CYP3A4ALOX15
SCHEMBL9087530 0.82 KMT2A (0.76) KMT2ASQLEMEN1CYP3A4ALOX15
SCHEMBL18972907 0.82 KMT2A (0.76) KMT2ASQLEMEN1CYP3A4ALOX15
SCHEMBL9446281 0.76 KMT2A (0.81) KMT2ASQLEMEN1CYP3A4ALOX15
SCHEMBL19571039 0.76 KMT2A (0.81) KMT2ASQLEMEN1CYP3A4ALOX15
SCHEMBL13129982 0.76 KMT2A (0.73) KMT2ASQLEMEN1CYP3A4ALOX15
SCHEMBL18095903 0.76 TSHR (0.39) KMT2ASQLEMEN1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7012120-B2 Reworkable compositions of oxirane(s) or thirane(s)-containing resin and curing agent HENKEL CORPORATION (US) 2006-03-14 US claimed
US-20050288458-A1 Reworkable thermosetting resin composition KLEMARCZYK PHILIP T 2005-12-29 US claimed
EP-1268457-A4 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORP (US) 2005-07-20 EP claimed
JP-2003529643-A 2003-10-07 JP claimed
US-20030073770-A1 Reworkable compositions of oxirane(s) or thirane(s)-containing resin and curing agent Henkel IP & Holding GmbH (DE) 2003-04-17 US claimed
EP-1268457-A1 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORPORATION (US) 2003-01-02 EP claimed
WO-2001074798-A1 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORPORATION (US) 2001-10-11 WO claimed
US-8053587-B2 for mounting onto a circuit board semiconductor devices HENKEL CORPORATION (US) 2011-11-08 US disclosed
US-20080214840-A1 Reworkable thermosetting resin composition HENKEL CORPORATION (US) 2008-09-04 US disclosed
US-7012120-B2 Reworkable compositions of oxirane(s) or thirane(s)-containing resin and curing agent HENKEL CORPORATION (US) 2006-03-14 US disclosed
US-20050288458-A1 Reworkable thermosetting resin composition KLEMARCZYK PHILIP T 2005-12-29 US disclosed
EP-1268457-A4 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORP (US) 2005-07-20 EP disclosed
US-20030073770-A1 Reworkable compositions of oxirane(s) or thirane(s)-containing resin and curing agent Henkel IP & Holding GmbH (DE) 2003-04-17 US disclosed
EP-1268457-A1 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORPORATION (US) 2003-01-02 EP disclosed
WO-2001074798-A1 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORPORATION (US) 2001-10-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080214840-A1 Reworkable thermosetting resin composition GSS, LSS, LRBA KMT2A 586/4885SQLE 2948/4885MEN1 4450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.