GSS

Glutathione synthetase · P48637 · GSS on Sugi Atlas →

0 patent compounds predicted against GSS, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to GSS by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Paracetamol Study in Patients With Low Muscle Mass PHASE4UNKNOWN
Supportive Measures in Treatment of Aluminum Phosphide Poisoning PHASE4COMPLETED
Cysteine Supplementation in Critically Ill Neonates PHASE2/PHASE3UNKNOWN
The Combined Effect of N-Acetyl Cysteine and Metformin in Polycystic Ovary Syndrome Patients PHASE3RECRUITING
Role of Antioxidants Supplementation in Chronic Pancreatitis PHASE3COMPLETED
Serine Supplementation for Obese Subjects With Fatty Liver Disease PHASE1/PHASE2COMPLETED
A Preliminary Study to Evaluate Cysteamine Therapy in Human Subjects With Non-Alcoholic Steatohepatitis (NASH) PHASE1/PHASE2COMPLETED
Effect of Melatonin in Patients With Diabetic Peripheral Neuropathy PHASE2RECRUITING
Prevent Cardiac Surgery Associated AKI Trial PHASE2RECRUITING
Sulforaphane in a New Jersey (NJ) Population of Individuals With Autism PHASE2ACTIVE_NOT_RECRUITING
N-Acetylcysteine for Neuroprotection in Parkinson's Disease PHASE1/PHASE2COMPLETED
The Effects of a Glutathione Precursor (FT061452),on Serum and Intracellular Glutathione Levels PHASE1COMPLETED
Tolerability of Enteral NAC in Infants PHASE1NOT_YET_RECRUITING
GSNOR Phenotyping/GSNO Challenge in Severe Asthma EARLY_PHASE1COMPLETED
Assessment of the Impact of N-acetylcysteine Supplementation on Physical Performance nanCOMPLETED
Review of French Cases of Glutathione Synthetase Deficiency nanUNKNOWN
Effect of Sulfur Amino Acid Depletion and Acetaminophen on Plasma Glutatione nanCOMPLETED
NAC Supplementation and Skeletal Muscle Performance nanCOMPLETED
Thiol/Disulphide Homeostasis in Unexplained Infertility nanCOMPLETED
Analysis of the Glutathione Cycle in Children With Rett Syndrome nanWITHDRAWN
Cancer and Hearing Loss Related in Children nanCOMPLETED
The Influence of Melatonin Supplementation in the Group of Persons Performing Competitive Sport. nanCOMPLETED
The Conversion of ENcapsulated GlucorAphanin, Gut Microbiota Phylogeny and gEnotype Study (ENGAGE) nanCOMPLETED
Oxidative Stress in Intestinal Metaplasia and Metabolic Syndrome nanUNKNOWN
Effects of Green Tea Extract (GTE) on Systemic Oxidative and Antioxidative Status in Chinese Patients With Stable Asthma nanCOMPLETED
SH-SS and GSH-GSSG Homeostasis in Post-stroke Patients nanCOMPLETED
Broccoli and Vascular Health Study nanCOMPLETED
Biological Evaluation of Dietary Supplement Liposomal Glutathione nanCOMPLETED
Supplementation of Oral Reduced Glutathione in Pediatric Cystic Fibrosis Patients nanCOMPLETED
Effect of SGLT2 Inhibitors on NAFLD in Type 2 Diabetic Patients with Diabetic Nephropathy nanNOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a GSS binder may also engage these)

ProteinNameSimilarity
P51855 1.000 P51855 →
P46413 1.000 P46413 →
Q8HXX5 1.000 Q8HXX5 →
Q5EAC2 1.000 Q5EAC2 →
P35668 0.990 P35668 →
Q9I7S8 0.977 Q9I7S8 →
Q4KLZ6 0.977 Q4KLZ6 →
PRMT5 Protein arginine N-methyltransferase 5 0.976 landscape →
Q5RBT4 0.975 Q5RBT4 →
Q9UDR5 0.975 Q9UDR5 →
A8E657 0.975 A8E657 →
Q68FX0 0.975 Q68FX0 →
Q28479 0.974 Q28479 →
Q9XGZ0 0.974 Q9XGZ0 →
B7J4G8 0.973 B7J4G8 →
Q5RCH4 0.973 Q5RCH4 →
G6PD Glucose-6-phosphate 1-dehydrogenase 0.973 landscape →
Q8BGQ7 0.973 Q8BGQ7 →
C4K7D7 0.973 C4K7D7 →
A7YW45 0.973 A7YW45 →
P05370 0.973 P05370 →
QTRT1 Queuine tRNA-ribosyltransferase catalytic subunit 1 0.973 landscape →
P70404 0.973 P70404 →
Q7M7H8 0.973 Q7M7H8 →
Q8VC30 0.973 Q8VC30 →
A5GFY8 0.973 A5GFY8 →
Q0J7N5 0.973 Q0J7N5 →
O55044 0.973 O55044 →
Q5RC02 0.972 Q5RC02 →
A6VPM2 0.972 A6VPM2 →