Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13156203 | 0.94 | TSHR (0.36) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10298813 | 0.85 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15355900 | 0.85 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL13057759 | 0.85 | TSHR (0.42) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2367838 | 0.84 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17211881 | 0.84 | TSHR (0.39) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17069794 | 0.83 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11919878 | 0.83 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19239961 | 0.83 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL13855109 | 0.82 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455599-B2 | Asymmetric low molecular weight siloxanes with one functional group | GELEST TECHNOLOGIES, INC. (US) | 2013-06-04 | — | — | US | disclosed |
| US-20100298591-A1 | ASYMMETRIC LOW MOLECULAR WEIGHT SILOXANES WITH ONE FUNCTIONAL GROUP | GELEST, INC. (US) | 2010-11-25 | — | — | US | disclosed |
| US-20080269429-A1 | LOW MOLECULAR WEIGHT SILOXANES WITH ONE FUNCTIONAL GROUP | GELEST, INC. (US) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298591-A1 | ASYMMETRIC LOW MOLECULAR WEIGHT SILOXANES WITH ONE FUNCTIONAL GROUP | ILK, LASP1, PCNA | TSHR 3911/4885THRB 3028/4885POLB 3239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.