⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26791451 | 0.93 | INMT (0.39) | — | |
| SCHEMBL9945748 | 0.86 | — | — | |
| SCHEMBL25758669 | 0.77 | INMT (0.31) | — | |
| SCHEMBL27420473 | 0.77 | INMT (0.30) | — | |
| SCHEMBL14818718 | 0.74 | — | — | |
| SCHEMBL13057847 | 0.70 | — | — | |
| SCHEMBL266971 | 0.69 | — | — | |
| SCHEMBL24899342 | 0.67 | — | — | |
| SCHEMBL266970 | 0.67 | — | — | |
| SCHEMBL82580 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3680272-B1 | CATALYST SYSTEM FOR THE PREPARATION OF HIGH-MOLECULAR WEIGHT POLYETHER AND APPLICATION THEREOF | UNIV STUTTGART (DE) | 2023-08-23 | — | — | EP | disclosed |
| WO-2020144293-A1 | CATALYST SYSTEM FOR THE PREPARATION OF HIGH-MOLECULAR WEIGHT POLYETHER AND APPLICATION THEREOF | Universität Stuttgart (DE) | 2020-07-16 | — | — | WO | disclosed |
| EP-3680272-A1 | CATALYST SYSTEM FOR THE PREPARATION OF HIGH-MOLECULAR WEIGHT POLYETHER AND APPLICATION THEREOF | Universität Stuttgart (DE) | 2020-07-15 | — | — | EP | disclosed |
| EP-3124561-A1 | ACTIVE ENERGY RAY-CURABLE INKJET INK | Toyo Ink SC Holdings Co., Ltd. (JP) | 2017-02-01 | — | — | EP | disclosed |
| US-8901141-B2 | Tricyclic compounds having corticotropin-releasing factor antagonistic activity and pharmaceutical compositions containing them | TAKEDA PHARMACEUTICAL COMPANY, LIMITED (JP) | 2014-12-02 | — | — | US | disclosed |
| US-8785460-B2 | Tricyclic compounds and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-07-22 | — | — | US | disclosed |
| US-20100298287-A1 | TRICYCLIC COMPOUNDS HAVING CORTICOTROPIN-RELEASING FACTOR ANTAGONISTIC ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-11-25 | — | — | US | disclosed |
| US-7655804-B2 | N-[(1S)-3-{(2Z)-2-[(4R)-3,4-dimethyl-1,3-thiazolidin-2-ylidene]hydrazino}-2,3-dioxo-1-(tetrahydro-2H-pyran-4-yl)propyl]cycloheptanecarboxamide; cysteine protease inhibitors; for the treatment of inflammatory, immune, ischemic, respiratory,circulatory, neuronal, blood, hepatic and metabolic diseases | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-02-02 | — | — | US | disclosed |
| US-20090186879-A1 | TRICYCLIC COMPOUNDS AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-07-23 | — | — | US | disclosed |