Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 5/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13002070 | 0.82 | SMN1; SMN2 (0.34) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL13002076 | 0.81 | KDM4E (0.33) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL13002079 | 0.81 | TOP2A (0.37) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL13002080 | 0.81 | SMN1; SMN2 (0.33) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL13002072 | 0.81 | SMN1; SMN2 (0.33) | PPARASMN1; SMN2KDM4ERAB9ANPC1 | |
| SCHEMBL13002077 | 0.81 | SMN1; SMN2 (0.33) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL13002082 | 0.80 | SMN1; SMN2 (0.32) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL13002074 | 0.80 | TOP2A (0.35) | SMN1; SMN2KDM4ERAB9ANPC1POLB | |
| SCHEMBL2822722 | 0.77 | JAK1 (0.42) | PPARARAB9ANPC1PPARDPPARG | |
| SCHEMBL2822685 | 0.76 | PIK3CD (0.44) | SMN1; SMN2KDM4EGAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100311966-A1 | IMIDAZOLE CARBONYL COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311966-A1 | IMIDAZOLE CARBONYL COMPOUND | TOP1, TOP2B, TOP2A | PPARA 2960/4885SMN1; SMN2 4001/4885KDM4E 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.