Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4856298 | 0.97 | GAA (0.43) | GAAGFERHPGDHTTSMN1; SMN2 | |
| SCHEMBL19034711 | 0.94 | KDM4E (0.53) | GAAGFERHPGDHTTSMN1; SMN2 | |
| SCHEMBL19429316 | 0.92 | KDM4E (0.50) | GAAGFERHPGDHTTSMN1; SMN2 | |
| SCHEMBL1981658 | 0.92 | KDM4E (0.50) | GAAGFERHPGDHTTSMN1; SMN2 | |
| SCHEMBL29450664 | 0.92 | KDM4E (0.50) | GAAGFERHPGDHTTSMN1; SMN2 | |
| SCHEMBL13301590 | 0.92 | KDM4E (0.50) | GAAGFERHPGDHTTSMN1; SMN2 | |
| SCHEMBL12856945 | 0.92 | KDM4E (0.50) | GAAGFERHPGDHTTSMN1; SMN2 | |
| SCHEMBL1144158 | 0.92 | KDM4E (0.50) | GAAGFERHPGDHTTSMN1; SMN2 | |
| SCHEMBL30707866 | 0.91 | GAA (0.45) | GAAGFERHPGDHTTSMN1; SMN2 | |
| SCHEMBL19788253 | 0.90 | KDM4E (0.49) | GAAGFERHPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130075670-A1 | AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS | PLEXTRONICS, INC. (US) | 2013-03-28 | — | — | US | disclosed |
| US-20130075670-A1 | AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS | PLEXTRONICS, INC. (US) | 2013-03-28 | — | — | US | disclosed |
| US-8283002-B2 | Aminobenzene compositions and related devices and methods | PLEXTRONICS, INC. (US) | 2012-10-09 | — | — | US | disclosed |
| US-8283002-B2 | Aminobenzene compositions and related devices and methods | PLEXTRONICS, INC. (US) | 2012-10-09 | — | — | US | disclosed |
| US-20100292399-A1 | AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS | PLEXTRONICS, INC. | 2010-11-18 | — | — | US | disclosed |
| US-20100292399-A1 | AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS | PLEXTRONICS, INC. | 2010-11-18 | — | — | US | disclosed |
| WO-2010059646-A2 | AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS | PLEXTRONICS, INC. (US) | 2010-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130075670-A1 | AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS | HLA-B, AAAS, SLCO2B1 | GAA 4187/4885GFER 394/4885HPGD 2014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.