SCHEMBL19788253

SCHEMBL19788253

Oc1ccc(N(c2ccc(-c3ccc(N(c4ccc(O)cc4)c4ccc5c(c4)c4ccccc4n5-c4ccccc4)cc3)cc2)c2ccc3c(c2)c2ccccc2n3-c2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.49
▸ ATM Q13315 1/20 0.49
▸ L3MBTL1 Q9Y468 1/20 0.49
▸ GAA P10253 1/20 0.42
▸ GFER P55789 1/20 0.42
▸ HPGD P15428 3/20 0.41
▸ HTT P42858 2/20 0.41
▸ LMNA P02545 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ KMT2A Q03164 4/20 0.40
▸ MEN1 O00255 3/20 0.40
▸ CYP1A2 P05177 2/20 0.40
▸ CYP3A4 P08684 2/20 0.40
▸ CYP2C9 P11712 2/20 0.40
▸ CYP2C19 P33261 2/20 0.40
▸ HSD17B10 Q99714 2/20 0.40
▸ CYP2D6 P10635 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ PKM P14618 1/20 0.40
▸ ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19034711 0.96 KDM4E (0.53) KDM4EATML3MBTL1GAAGFER
SCHEMBL12037168 0.95 KDM4E (0.49) KDM4EATML3MBTL1GAAGFER
SCHEMBL8928173 0.93 L3MBTL1 (0.56) KDM4EATML3MBTL1GAAGFER
SCHEMBL8928135 0.92 L3MBTL1 (0.55) KDM4EATML3MBTL1GAAGFER
SCHEMBL15964453 0.92 L3MBTL1 (0.55) KDM4EATML3MBTL1GAAGFER
SCHEMBL13724934 0.92 L3MBTL1 (0.55) KDM4EATML3MBTL1GAAGFER
SCHEMBL2699413 0.92 L3MBTL1 (0.55) KDM4EATML3MBTL1GAAGFER
SCHEMBL8928201 0.92 L3MBTL1 (0.55) KDM4EATML3MBTL1GAAGFER
SCHEMBL8928266 0.92 L3MBTL1 (0.55) KDM4EATML3MBTL1GAAGFER
SCHEMBL13725862 0.92 L3MBTL1 (0.55) KDM4EATML3MBTL1GAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230120805-A1 PHENYLCARBAZOLE-BASED COMPOUNDS AND FLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE AND FLAT PANEL DISPLAY DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2023-04-20 — — US disclosed
US-20200152884-A1 PHENYLCARBAZOLE-BASED COMPOUNDS AND FLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE AND FLAT PANEL DISPLAY DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2020-05-14 — — US disclosed
US-10573821-B2 Phenylcarbazole-based compounds and fluorene-based compounds and organic light emitting device and flat panel display device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-25 — — US disclosed
US-20190157568-A1 PHENYLCARBAZOLE-BASED COMPOUNDS AND FLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE AND FLAT PANEL DISPLAY DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2019-05-23 — — US disclosed
US-10211406-B2 Phenylcarbazole-based compounds and fluorene-based compounds and organic light emitting device and flat panel display device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-02-19 — — US disclosed
US-20180159047-A1 PHENYLCARBAZOLE-BASED COMPOUNDS AND FLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE AND FLAT PANEL DISPLAY DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2018-06-07 — — US disclosed
US-9917258-B2 Phenylcarbazole-based compounds and fluorene-based compounds and organic light emitting device and flat panel display device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-13 — — US disclosed
US-9876175-B2 Organic electroluminescent element, material for organic electroluminescent element, and light emitting device, display device and lighting device each using organic electroluminscent element UDC IRELAND LIMITED (IE) 2018-01-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200152884-A1 PHENYLCARBAZOLE-BASED COMPOUNDS AND FLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE AND FLAT PANEL DISPLAY DEVICE COMPRISING THE SAME CYP3A4, PPOX, CYP2C19 KDM4E 655/4885ATM 4200/4885L3MBTL1 1125/4885
US-20230120805-A1 PHENYLCARBAZOLE-BASED COMPOUNDS AND FLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE AND FLAT PANEL DISPLAY DEVICE COMPRISING THE SAME CYP3A4, PPOX, CYP2C19 KDM4E 655/4885ATM 4200/4885L3MBTL1 1125/4885
US-20180159047-A1 PHENYLCARBAZOLE-BASED COMPOUNDS AND FLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE AND FLAT PANEL DISPLAY DEVICE COMPRISING THE SAME CYP3A4, CYP2C19, PPOX KDM4E 652/4885ATM 4416/4885L3MBTL1 1043/4885
US-10573821-B2 Phenylcarbazole-based compounds and fluorene-based compounds and organic light emitting device and flat panel display device comprising the same CYP3A4, PPOX, CYP2C19 KDM4E 655/4885ATM 4200/4885L3MBTL1 1125/4885
US-20190157568-A1 PHENYLCARBAZOLE-BASED COMPOUNDS AND FLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE AND FLAT PANEL DISPLAY DEVICE COMPRISING THE SAME CYP3A4, PPOX, CYP2C19 KDM4E 655/4885ATM 4200/4885L3MBTL1 1125/4885
US-10211406-B2 Phenylcarbazole-based compounds and fluorene-based compounds and organic light emitting device and flat panel display device comprising the same CYP3A4, CYP2C19, PPOX KDM4E 652/4885ATM 4416/4885L3MBTL1 1043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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