Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13060225 | 0.88 | KDM4E (0.57) | KDM4EMAPTNPC1RAB9AGAA | |
| SCHEMBL17112792 | 0.86 | KDM4E (0.64) | KDM4EMAPTNPC1RAB9AGAA | |
| SCHEMBL13060221 | 0.86 | KDM4E (0.54) | KDM4EMAPTNPC1RAB9AGAA | |
| SCHEMBL17112791 | 0.86 | KDM4E (0.64) | KDM4EMAPTNPC1RAB9AGAA | |
| SCHEMBL19011313 | 0.84 | ALDH1A1 (0.59) | KDM4EMAPTNPC1RAB9AGAA | |
| SCHEMBL13060202 | 0.81 | MAPT (0.72) | KDM4EMAPTRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL171857 | 0.80 | APP (0.69) | MAPTNPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL18475585 | 0.80 | APP (0.69) | MAPTNPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL9351127 | 0.79 | NPC1 (0.53) | KDM4EMAPTNPC1RAB9AGAA | |
| SCHEMBL13004000 | 0.79 | NPC1 (0.53) | KDM4EMAPTNPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851503-B2 | Thrombopoetin receptor activator and process for producing the same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-12-14 | — | — | US | disclosed |