Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 13/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 13/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 13/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13061009 | 0.88 | OPRM1 (0.46) | OPRM1OPRD1OPRK1NPC1CXCR4 | |
| SCHEMBL13005541 | 0.84 | OPRM1 (0.44) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL172762 | 0.79 | OPRM1 (0.47) | OPRM1OPRD1OPRK1CXCR4 | |
| SCHEMBL12126132 | 0.77 | OPRM1 (0.54) | OPRM1OPRD1OPRK1 | |
| SCHEMBL12772084 | 0.76 | TAAR1 (0.48) | — | |
| SCHEMBL12126130 | 0.75 | OPRM1 (0.56) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28584835 | 0.75 | IDO1 (0.48) | — | |
| SCHEMBL13005432 | 0.73 | OPRM1 (0.44) | OPRM1OPRD1OPRK1CXCR4 | |
| SCHEMBL10039132 | 0.73 | OPRM1 (0.54) | OPRM1OPRD1OPRK1 | |
| SCHEMBL19961503 | 0.73 | OPRM1 (0.75) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |