Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.55 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 5/20 | 0.47 |
| ▸ | ACHE | P22303 | 4/20 | 0.47 |
| ▸ | HTR7 | P34969 | 4/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14027605 | 0.87 | CALM1 (0.74) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL4823756 | 0.86 | KDM4E (0.65) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL4821016 | 0.86 | CALM1 (0.54) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL14027584 | 0.86 | CALM1 (0.54) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL14027595 | 0.85 | KDM4E (0.55) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL13005561 | 0.84 | CALM1 (0.52) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL13060673 | 0.84 | CALM1 (0.50) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL14027599 | 0.82 | KDM4E (0.55) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL10039143 | 0.82 | CALM1 (0.64) | CALM1CAMKK2KDM4EALDH1A1TSHR | |
| SCHEMBL13061135 | 0.78 | CALM1 (0.44) | CALM1CAMKK2KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |