Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | TARS1 | P26639 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15941776 | 1.00 | SPHK1 (0.41) | SPHK1CTSCTARS1TSHRANPEP | |
| SCHEMBL14611830 | 1.00 | SPHK1 (0.41) | SPHK1CTSCTARS1TSHRANPEP | |
| SCHEMBL15941449 | 1.00 | SPHK1 (0.41) | SPHK1CTSCTARS1TSHRANPEP | |
| Hydrochloric Acid SCHEMBL15941251 | 0.98 | SPHK1 (0.40) | SPHK1CTSCTARS1TSHRANPEP | |
| Hydrochloric Acid SCHEMBL15941253 | 0.98 | SPHK1 (0.40) | SPHK1CTSCTARS1TSHRANPEP | |
| SCHEMBL8265865 | 0.84 | DPP4 (0.47) | TSHRDPP7USP2SLC15A1MMP1 | |
| SCHEMBL17832776 | 0.84 | DPP4 (0.47) | TSHRDPP7USP2SLC15A1MMP1 | |
| SCHEMBL12257899 | 0.84 | DPP4 (0.47) | TSHRDPP7USP2SLC15A1MMP1 | |
| SCHEMBL14611659 | 0.81 | SPHK1 (0.38) | SPHK1CTSCTARS1TSHRANPEP | |
| SCHEMBL12259750 | 0.80 | TERT (0.46) | TSHRDPP7USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100323990-A1 | SHIP 1 MODULATOR PRODRUGS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323990-A1 | SHIP 1 MODULATOR PRODRUGS | PPM1D, PPM1G, PPM1F | SPHK1 1016/4885CTSC 1477/4885TARS1 947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.