Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 11/20 | 0.38 |
| ▸ | PGR | P06401 | 11/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.34 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13062185 | 0.85 | SRD5A2 (0.40) | ARPGRNR3C2SRD5A2MEN1 | |
| SCHEMBL13474760 | 0.85 | SRD5A2 (0.40) | ARPGRNR3C2SRD5A2MEN1 | |
| SCHEMBL13062190 | 0.84 | AR (0.34) | ARPGRNR3C2SRD5A2SLC6A4 | |
| SCHEMBL13013736 | 0.80 | AR (0.61) | ARPGRNR3C2 | |
| SCHEMBL4111659 | 0.78 | SRD5A2 (0.37) | ARPGRNR3C2SRD5A2SLC6A4 | |
| SCHEMBL9222367 | 0.76 | AR (0.39) | ARPGRNR3C2SRD5A2SLC6A4 | |
| SCHEMBL9222376 | 0.76 | AR (0.39) | ARPGRNR3C2SRD5A2SLC6A4 | |
| SCHEMBL13062191 | 0.75 | PGR (0.66) | ARPGRNR3C2SLC6A4MEN1 | |
| SCHEMBL987024 | 0.74 | SRD5A2 (0.40) | ARPGRNR3C2SRD5A2SLC6A4 | |
| SCHEMBL10631847 | 0.73 | SRD5A2 (0.42) | ARPGRNR3C2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317632-A1 | 17-(1'PROPENYL)-17-3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317632-A1 | 17-(1'PROPENYL)-17-3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | NR5A1, CYP19A1, CYP17A1 | AR 44/4885PGR 8/4885NR3C2 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.