Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14723724 | 0.87 | MCL1 (0.46) | NT5EMCL1MMP1PTPN1MAOA | |
| SCHEMBL10135416 | 0.84 | NT5E (0.43) | NT5EMCL1MMP1PTPN1MAOA | |
| SCHEMBL10181459 | 0.84 | ELANE (0.51) | NT5EMCL1MMP1PTPN1MAOA | |
| SCHEMBL16167898 | 0.84 | ELANE (0.51) | NT5EMCL1MMP1PTPN1MAOA | |
| SCHEMBL10135420 | 0.84 | ELANE (0.51) | NT5EMCL1MMP1PTPN1MAOA | |
| SCHEMBL10181803 | 0.82 | NT5E (0.44) | NT5EMCL1MMP1PTPN1MAOA | |
| SCHEMBL10182090 | 0.82 | PGAM1 (0.49) | NT5EMCL1MMP1PTPN1MAOA | |
| SCHEMBL10135412 | 0.81 | NT5E (0.41) | NT5EMCL1MMP1PTPN1MAOA | |
| SCHEMBL10182036 | 0.79 | NT5E (0.40) | NT5EMCL1MMP1PTPN1MAOA | |
| SCHEMBL14723716 | 0.78 | MCL1 (0.38) | NT5EMCL1MEN1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383088-B2 | Coumestan-like antioxidants and UV absorbants | BASF SE (DE) | 2013-02-26 | — | — | US | disclosed |
| US-20100330009-A1 | COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS | CIBA CORPORATION (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100330009-A1 | COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS | TYR, NQO1, SIRT3 | NT5E 3169/4885MCL1 3833/4885MMP1 1333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.