Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3078747 | 0.75 | KMT2A (0.39) | KMT2AL3MBTL1GAAALDH1A1ALOX15 | |
| SCHEMBL8234342 | 0.74 | GAA (0.41) | KMT2AL3MBTL1GAAALDH1A1HSD17B10 | |
| SCHEMBL9796453 | 0.70 | KDM4E (0.40) | KMT2AL3MBTL1GAAALDH1A1MAPT | |
| SCHEMBL19746316 | 0.70 | GAA (0.38) | KMT2AL3MBTL1GAAALDH1A1HSD17B10 | |
| SCHEMBL14559644 | 0.69 | GAA (0.36) | KMT2AL3MBTL1GAAALDH1A1USP2 | |
| SCHEMBL6023769 | 0.68 | TSHR (0.40) | KMT2AL3MBTL1GAAALDH1A1MAPT | |
| SCHEMBL597365 | 0.63 | KMT2A (0.51) | KMT2AL3MBTL1GAAALDH1A1MAPT | |
| SCHEMBL27300102 | 0.62 | GAA (0.43) | KMT2AL3MBTL1GAAALDH1A1HSD17B10 | |
| SCHEMBL19746544 | 0.62 | SMN1; SMN2 (0.38) | KMT2AL3MBTL1GAAALDH1A1USP2 | |
| SCHEMBL2048291 | 0.62 | GAA (0.39) | KMT2AL3MBTL1GAAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260839-A2 | Combination therapy using 1-aminocyclohexane derivatives and acetylcholinesterase inhibitors | Merz Pharma GmbH & Co. KGaA (DE) | 2010-12-15 | — | — | EP | disclosed |