Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19746780 | 0.83 | USP2 (0.41) | SMN1; SMN2USP2NR1H2HPGDEPHX2 | |
| SCHEMBL23326750 | 0.83 | KMT2A (0.42) | SMN1; SMN2USP2ADORA1KMT2AL3MBTL1 | |
| SCHEMBL24906856 | 0.81 | KMT2A (0.40) | SMN1; SMN2USP2ADORA1KMT2AL3MBTL1 | |
| SCHEMBL980372 | 0.80 | ADORA1 (0.39) | SMN1; SMN2USP2ADORA1KMT2AL3MBTL1 | |
| SCHEMBL18497293 | 0.80 | KMT2A (0.39) | SMN1; SMN2USP2ADORA1KMT2AL3MBTL1 | |
| SCHEMBL31088801 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2USP2ADORA1KMT2AL3MBTL1 | |
| SCHEMBL22655647 | 0.78 | L3MBTL1 (0.39) | SMN1; SMN2USP2ADORA1KMT2AL3MBTL1 | |
| SCHEMBL18044513 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2USP2ADORA1KMT2AL3MBTL1 | |
| SCHEMBL34473910 | 0.77 | KMT2A (0.37) | SMN1; SMN2USP2ADORA1KMT2AL3MBTL1 | |
| SCHEMBL30722411 | 0.77 | ADORA1 (0.37) | SMN1; SMN2USP2ADORA1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017223349-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2017-12-28 | — | — | WO | disclosed |