SCHEMBL1306343

SCHEMBL1306343

O=[N+]([O-])c1ccsc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28476867 0.82 ALDH1A1 (0.48)
Ethoxycarbonyl Group SCHEMBL27731816 0.80 ALDH1A1 (0.36)
SCHEMBL11826120 0.76 PDE7A (0.43)
SCHEMBL872076 0.74 PDE7A (0.46)
SCHEMBL9375139 0.73
SCHEMBL4648229 0.73
SCHEMBL10933026 0.73
SCHEMBL5841002 0.73
SCHEMBL4648233 0.73
SCHEMBL7459715 0.72 TSHR (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250326790-A1 PEPTIDES BINDING TO HYPOXIA INDUCIBLE FACTORS AND THEIR USE UNIVERSITY OF SOUTHAMPTON (GB) 2025-10-23 US claimed
EP-4298110-A1 PEPTIDES BINDING TO HYPOXIA INDUCIBLE FACTORS AND THEIR USE UNIVERSITY OF SOUTHAMPTON (GB) 2024-01-03 EP claimed
WO-2022180410-A1 PEPTIDES BINDING TO HYPOXIA INDUCIBLE FACTORS AND THEIR USE UNIVERSITY OF SOUTHAMPTON (GB) 2022-09-01 WO claimed
US-20250326790-A1 PEPTIDES BINDING TO HYPOXIA INDUCIBLE FACTORS AND THEIR USE UNIVERSITY OF SOUTHAMPTON (GB) 2025-10-23 US disclosed
WO-2025090758-A1 AHR AGONISTS ELI LILLY AND COMPANY (US) 2025-05-01 WO disclosed
CN-119330982-A Azetidine compound and medical application thereof 中国科学院上海药物研究所 2025-01-21 CN disclosed
EP-4298110-A1 PEPTIDES BINDING TO HYPOXIA INDUCIBLE FACTORS AND THEIR USE UNIVERSITY OF SOUTHAMPTON (GB) 2024-01-03 EP disclosed
CN-116535340-A Substituted N-aryl-1-naphthylamine compound, preparation method and pharmaceutical application thereof 中国医学科学院药物研究所 2023-08-04 CN disclosed
WO-2022180410-A1 PEPTIDES BINDING TO HYPOXIA INDUCIBLE FACTORS AND THEIR USE UNIVERSITY OF SOUTHAMPTON (GB) 2022-09-01 WO disclosed
US-20220081427-A1 INHIBITORS OF JUN N-TERMINAL KINASE IMAGO PHARMACEUTICALS, INC. (US) 2022-03-17 US disclosed
US-20200277285-A1 INHIBITORS OF JUN N-TERMINAL KINASE IMAGO PHARMACEUTICALS, INC. (US) 2020-09-03 US disclosed
WO-1999028305-A1 FUNGICIDAL CYCLIC AMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-06-10 WO disclosed
US-5885935-A Sulfonamide herbicides AGREVO UK LIMITED (GB) 1999-03-23 US disclosed
WO-1998023156-A1 METHYL SUBSTITUTED FUNGICIDES AND ARTHROPODICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-06-04 WO disclosed
EP-0625970-B1 SULFONAMIDE HERBICIDES AGREVO UK LTD (GB) 1997-09-17 EP disclosed
US-5559081-A Sulfonamide herbicides AGREVO UK LIMITED (GB) 1996-09-24 US disclosed
EP-0625970-A1 SULFONAMIDE HERBICIDES. AGREVO UK LTD (GB) 1994-11-30 EP disclosed
US-5217982-A Compounds having antihypertensive properties RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1993-06-08 US disclosed
WO-1993009099-A2 SULFONAMIDE HERBICIDES AGREVO UK LIMITED (GB) 1993-05-13 WO disclosed
US-4061764-A Certain O-substituted thiophene oxime carbamates used as antibacterial and antifungal agents ABBOTT LABORATORIES (US) 1977-12-06 US disclosed