Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18395904 | 0.91 | CA2 (0.56) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL6943821 | 0.91 | CA2 (0.56) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL7042446 | 0.88 | CA2 (0.53) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL10441415 | 0.87 | CA2 (0.51) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL13651150 | 0.85 | CA2 (0.50) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL10032797 | 0.85 | CA2 (0.54) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL4132454 | 0.85 | CA2 (0.50) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL3685538 | 0.85 | CA2 (0.53) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL461346 | 0.84 | CA2 (0.56) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL6575404 | 0.84 | CA2 (0.56) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858606-B2 | Triterpenoid derivatives | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2010-12-28 | — | — | US | disclosed |