Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778131 | 0.90 | TLR8 (0.33) | CYP1A2PTGER1MEN1CYP2C9CYP2C19 | |
| SCHEMBL3787471 | 0.88 | CYP1A2 (0.37) | CYP1A2S1PR3PTGER1MEN1CYP2C9 | |
| SCHEMBL13063655 | 0.85 | CYP1A2 (0.35) | CYP1A2 | |
| SCHEMBL8778052 | 0.84 | S1PR3 (0.37) | CYP1A2S1PR3PTGER1MEN1CYP2C9 | |
| SCHEMBL8777743 | 0.82 | CYP1A2 (0.38) | CYP1A2MEN1CYP2C9CYP2C19KMT2A | |
| SCHEMBL8777799 | 0.80 | PTGER1 (0.39) | CYP1A2PTGER1MEN1CYP2C9CYP2C19 | |
| SCHEMBL8778306 | 0.80 | SMN1; SMN2 (0.46) | CYP1A2PTGER1MEN1CYP2C9CYP2C19 | |
| SCHEMBL3787877 | 0.78 | CYP1A2 (0.39) | CYP1A2MEN1KMT2ASCN9A | |
| SCHEMBL13063428 | 0.78 | CYP1A2 (0.37) | CYP1A2KMT2ASCN9A | |
| SCHEMBL8777776 | 0.78 | NPC1 (0.40) | CYP1A2S1PR3PTGER1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136475-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-12-02 | — | — | WO | disclosed |