SCHEMBL13063655

SCHEMBL13063655

C#Cc1ccccc1Cc1cccc(-c2ncc3ccccc3n2)n1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.35
PDE10A Q9Y233 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8777975 0.88 TLR8 (0.36) CYP1A2PDE10A
SCHEMBL13063656 0.85 CYP1A2 (0.34) CYP1A2
SCHEMBL3787471 0.84 CYP1A2 (0.37) CYP1A2
SCHEMBL13063428 0.81 CYP1A2 (0.37) CYP1A2PDE10A
SCHEMBL3787877 0.81 CYP1A2 (0.39) CYP1A2
SCHEMBL8777776 0.81 NPC1 (0.40) CYP1A2PDE10A
SCHEMBL8778000 0.81 USP1 (0.40)
SCHEMBL8778052 0.80 S1PR3 (0.37) CYP1A2
SCHEMBL8778131 0.79 TLR8 (0.33) CYP1A2
SCHEMBL8778057 0.79 SCN9A (0.40) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010136475-A1 SUBSTITUTED QUINAZOLINES AS FUNGICIDES SYNGENTA PARTICIPATIONS AG (CH) 2010-12-02 WO disclosed