Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
| ▸ | CD44 | P16070 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 3/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12506889 | 1.00 | KDM1A (0.41) | KDM1AALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL14712000 | 0.79 | KDM1A (0.42) | KDM1AALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL25027774 | 0.72 | CD44 (0.38) | KDM1AALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL20687392 | 0.71 | KDM1A (0.46) | KDM1AALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL829495 | 0.71 | KDM1A (0.44) | KDM1AALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL22989888 | 0.67 | HTR5A (0.37) | KDM1AALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL20445640 | 0.65 | KDM1A (0.47) | KDM1AALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL598625 | 0.65 | BCL2L1 (0.58) | ALDH1A1LMNAHTTALOX12BCL2L1 | |
| SCHEMBL29892288 | 0.65 | BCL2L1 (0.52) | ALDH1A1LMNAALOX12BCL2L1BAD | |
| SCHEMBL30717272 | 0.65 | BCL2L1 (0.58) | ALDH1A1LMNAHTTALOX12BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258690-B1 | Tricyclic amines as intermediates in the synthesis of fungicidal carboxamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-20 | — | — | EP | disclosed |
| EP-2258690-A1 | Tricyclic amines as intermediates in the synthesis of fungicidal carboxamide derivatives | Syngenta Participations AG (CH) | 2010-12-08 | — | — | EP | disclosed |