Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15609263 | 0.89 | KMT2A (0.71) | KMT2APOLBHSD17B10ALDH1A1HTT | |
| SCHEMBL12793678 | 0.86 | KMT2A (0.75) | KMT2APOLBHSD17B10ALDH1A1HTT | |
| SCHEMBL19392334 | 0.86 | KMT2A (0.75) | KMT2APOLBHSD17B10ALDH1A1MEN1 | |
| SCHEMBL9941503 | 0.86 | KMT2A (0.70) | KMT2APOLBHSD17B10ALDH1A1HTT | |
| SCHEMBL31681308 | 0.84 | KMT2A (0.68) | KMT2APOLBHSD17B10ALDH1A1HTT | |
| SCHEMBL19392499 | 0.84 | KMT2A (0.68) | KMT2APOLBHSD17B10ALDH1A1HTT | |
| SCHEMBL9941840 | 0.83 | MAPT (0.67) | KMT2APOLBHSD17B10ALDH1A1HTT | |
| SCHEMBL12792966 | 0.83 | KMT2A (0.67) | KMT2APOLBHSD17B10ALDH1A1HTT | |
| SCHEMBL14380624 | 0.83 | L3MBTL1 (0.60) | KMT2APOLBALDH1A1HTTMEN1 | |
| SCHEMBL15609188 | 0.82 | KMT2A (0.69) | KMT2APOLBHSD17B10ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258356-A2 | CHEMICAL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST DENGUE VIRUS AND OTHER FLAVIVIRUSES | Centro De Ingenieria Genetica Y Biotecnologia (CU) | 2010-12-08 | — | — | EP | disclosed |