Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 14/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | PTGFR | P43088 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2712142 | 0.88 | MBNL1 (0.50) | MBNL1DHODHADORA2ACSNK2A2CSNK2B | |
| SCHEMBL13063651 | 0.86 | MBNL1 (0.51) | MBNL1DHODHCSNK2A2CSNK2BDHFR | |
| SCHEMBL13063652 | 0.85 | ADORA2A (0.57) | MBNL1DHODHADORA2ADHFRALKBH5 | |
| SCHEMBL2126776 | 0.77 | ADORA2A (0.55) | MBNL1DHODHADORA2ADHFRALKBH5 | |
| SCHEMBL13063627 | 0.77 | MBNL1 (0.55) | MBNL1DHODHADORA2A | |
| SCHEMBL2126572 | 0.76 | DHODH (0.48) | MBNL1DHODHDHFRALKBH5 | |
| SCHEMBL2124097 | 0.76 | APEX1 (0.52) | MBNL1DHODH | |
| SCHEMBL2123544 | 0.74 | ADORA2A (0.53) | MBNL1DHODHADORA2ADHFRALKBH5 | |
| SCHEMBL2123690 | 0.74 | ADORA2A (0.53) | MBNL1DHODHADORA2ADHFRALKBH5 | |
| SCHEMBL26708531 | 0.73 | MBNL1 (0.48) | MBNL1DHODHADORA2ACSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331293-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | AMGEN INC. (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331293-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | MCL1, MALT1, BCL9 | MBNL1 1476/4885DHODH 3503/4885ADORA2A 1363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.