Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3278629 | 0.93 | LMNA (0.61) | LMNASMN1; SMN2HTTKCNA5KMT2A | |
| SCHEMBL302271 | 0.89 | LMNA (0.68) | LMNASMN1; SMN2HTTKMT2AHPGD | |
| SCHEMBL13065013 | 0.88 | CNR2 (0.61) | LMNASMN1; SMN2HTTKMT2AHPGD | |
| SCHEMBL2813139 | 0.86 | LMNA (0.62) | LMNASMN1; SMN2HTTKMT2AHPGD | |
| SCHEMBL13065037 | 0.86 | LMNA (0.63) | LMNASMN1; SMN2HTTKMT2AHPGD | |
| SCHEMBL13064468 | 0.84 | LMNA (0.62) | LMNASMN1; SMN2HTTKMT2AHPGD | |
| SCHEMBL13064473 | 0.84 | LMNA (0.65) | LMNASMN1; SMN2HTTKMT2AHPGD | |
| SCHEMBL3282269 | 0.83 | LMNA (0.68) | LMNASMN1; SMN2HTTKCNA5KMT2A | |
| SCHEMBL1711134 | 0.83 | LMNA (0.63) | LMNASMN1; SMN2HTTKMT2AHPGD | |
| SCHEMBL13064480 | 0.82 | LMNA (0.65) | LMNASMN1; SMN2HTTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130638-A1 | SULFONAMIDE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | EVOTEC AG (DE) | 2010-11-18 | — | — | WO | disclosed |